Overcome Male Infertility - What is Sperm-Ubiquitin Tag Immunoassay (SUTI)?

 

As mentioned in previous articles, infertility is defined as inability of a couple to conceive after 12 months of unprotected intercourse or can not carry the pregnancy to term. Has over 5 million couples in the United States and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist. In this article, we will discuss what is male infertility sperm ubiquitin tag immunoassay (SUTI)?   I. DefinitionThe test is to detect inherited disorder fertility of male sterility to avoid unnecessaryfertility treatments for women.   II. ProcedureThe sperm semen of male infertility in the clinical laboratory and the surface of the sperm is analyzed to ubiquintin which is a small highly conserved regulatory protein that is expressed ubiquitously in complex structures enclosed within membranes.  III. DiagnosisFrom ubiquitnin is considered a universal marker of sperm abnormalities, including head and defects in the sperm tail and contaminants such as sperm spermatid, leukocytes and cellular debris.The semen sample is screened by immunofluorescence and cytometry, where A is shown increasing the binding of anti-ubiquitin antibodies on the surface of sperm to flow, the sperm sample is considered an anomaly which increases the risk of becasues infertility sperm ubiquitin levels have been associated with reduced fertility or infertility.  This test is still under developed, if proven successful state, not only helps to avoid many unnecessary   treatments for some infertile, but also helps remove damaged sperm sample sperm before fertilization in vitro and CAPI.