Wednesday, February 25, 2015

Overcome Female Infertility - What are Radioimmunoassays (RIAs)?


As mentioned in previous articles, infertility is defined as inability of a couple to conceive after 12 months of unprotected intercourse or can not carry the pregnancy to term. Has over 5 million couples in the United States and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist. In this article, we will discuss what is female infertility radioimmunoassay (RIA)?   I. DefinitionRadioimmunoassay (RIA) is a very sensitive medical technique used to measure concentrations of antigens, such as quantifying the inhibition of binding or binding of a radiolabeled antibody to a substance that helps your doctor to determine that infertility is not or caused by a hormonal imbalance during the menstrual cycle.   II. ProcedureBy mixing a known amount of an antigen and antibody in the serum sample from a patient containing an unknown amount, sufficient to measure the interaction of testosterone, LH, FSH, prolactin hormones.    III. DiagnosisAfter the uterine lining and the end of the previous menstrual cycle is removed. Increased estrogen indicate that menstrual cycle begins again. The levels of estrogen to stimulate hypothalamic gonadotropin releasing hormone secret (GnRH), which helps stimulate the pituitary gland to secret (FSH) for the production of eggs by the ovaries. When the egg is mature, the production of luteinizing hormone (LH) causes the mature egg being extruded by the ovaries few days before ovulation and allows the neck to produce sperm mucus friendly and progesterone levels increase to soften the uterine lining for implantation of the fertilized embryo that if the lining of the uterus is shed and prepare the next menstrual cycle. Everything that went wrong in the secretion of hormones during this process influence the quantification of inhibition of binding or binding that can be detected by radiolabeled substance to an antibody.   IV. RiskThere are no known risk.

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