Getting Pregnant At Any Age

  

Reading the experiences of patients with IVF-mini (also called mini-stim IVF) at sites of infertility blogging, it is clear that doctors do different things they call mini-IVF. Generally the patients describe an IVF cycle with limited drug to produce a limited number of eggs. This reduces the likely costs and benefits some patients, but do not give them all the benefits of IVF Mini-stim.
   Mini-stim IVF basically used the idea that the best eggs widely selected body (baby quality) before starting the cycle. Drugs improve the development of these eggs, but are used in small quantities that do not distort the follicle process and egg development. High doses of the drug may allow either chromosomally abnormal eggs to develop or lead to abnormalities in chromosomes of dividing process in the cytoplasm of the egg so that errors in chromosome division. Theoretically, very high doses of drugs can also cause the eggs to produce a biochemical imbalance that interfere with embryo development process.
   Fauser analyzed two groups of young patients who were randomized to receive low-dose or high induction of ovulation gonadotropin. All embryos were biopsy for PGD before transferring to determine the normal chromosome. Patients who received higher doses of the drug produced more embryos and eggs, but the number of normal embryos in both groups was the same.
  Animal studies have shown that the best odds eggs are evident before the start of the cycle. High doses of the drug can save part mainly eggs that were already destined not to become babies. Have more eggs during IVF makes everyone feel better, but not always improve the chances of success.
   We believe that this observation is particularly important in two main groups we see as the best candidates for IVF Mini-Stim: older women and couples with male factor or insulated tubes. Women with diminished ovarian reserve (FSH level diving, AMH under AFC) for some reason (age, surgery, genetics) are often treated with drugs containing FSH loading and still produce a handful of eggs. Normally, these eggs are morphologically reflect diminished ovarian reserve and high doses of gonadotropins. IVF Mini-Stim can probably produce as normal embryos with ovulation induction lot easier for the patient (less medication and follow-less) less than a third of the cost. The best data currently available suggest that pregnancy outcome is similar with the two approaches in this group of patients.
  Couples with good fertility underlying and the isolated sperm or tubal factors could produce at least one good egg with a Mini-stimulation cycle. Isolated male factor is entirely offset by the use of ICSI. Similarly, most tubal factors are compensated by placing the sperm with the egg. (Hydrosalpinx closed endometriosis and create other problems.) In this context, good egg is often all that is necessary for pregnancy. The pregnancy rate is probably higher with IVF IVF Mini-Stim classic, but not high enough to compensate for lower cost and cycle facility.
  Other patients choose to do IVF Mini-Stim, due to its low cost compared to conventional IVF or rather self-pay for expensive components of an infertility evaluation as laparoscopy. If Mini-Stim IVF fails, these patients can then follow and use conventional IVF.
   So how do you know if you do "mini-IVF" or "IVF-Lyte"? The main point is gonadotropin dose. For mini IVF, the dose is 1-2 ampoules of gonadotropins (75-150 units) per day. Oral medications are also often used to improve the patient's own production of FSH. If you use more drugs, then it is very likely to IVF-Lyte. Again IVF-Lyte can still be useful for patients, it's just different IVF Mini-Stim and philosophy underlying that is closer than the conventional IVF IVF Mini-Stim.